A Rare Case of Lymphomatoid Granulomatosis Occurring with Ulcerative Colitis

Lymphomatoid granulomatosis (LyG) is a rare type of angiocentric and angiodestructive lymphoproliferative disorder. We report a rare presentation of lymphomatoid granulomatosis in a patient with ulcerative colitis who’s been maintained on 6-Mercaptopurine for prolonged period of time. Although it is not clear whether inflammatory bowel disease (IBD) by itself is associated with such disorder or whether the use of immunosuppressive agents for the treatment of IBD induces EBV related lymphoproliferative disorder, it is important that clinicians are aware of the possible occurrence to ensure appropriate diagnostic evaluation and intervention.